Laboratory of genomic technologies

 

General description

For several years our laboratory has been devoted to apply genomic technologies to study human diseases and cellular models using multidisciplinary approaches such as biochemistry, biology, biotechnology and bioinformatics. In particular, we have gained a lot of experience in the study of gene expression profiles in various biological samples (cell lines and clinical tissues) using @microarray technology. In parallel, the group has been involved in the studying the genome variation (analysis of single nucleotide polymorphisms SNPs and copy number analysis) present in DNA samples obtained from human pathological specimens. Currently I am dealing with genome and transcriptome analysis using massive sequencing technologies (next generation sequencing, @NGS). Thanks to the presence of a multidisciplinary team and strong relationships with groups of bioinformatics (genomic unit ITB-CNR), we develop bioinformatics methodologies for analyzing and integrating complex biological data to study human diseases.

Main research lines

1. Study of human tumors (renal cell carcinoma, melanoma) and models of cell lines (ATCC lines and primary cells) using genome-wide technologies to analyze genes and microRNA (gene expression profiling, microarrays): oncogenomics field
2. Study of rare diseases using genomics technologies such as microarray (SNP array) and deep sequencing (next generation sequencing): genomics field
3. Biological effects and human health impacts of ultrafine particles source
4. Assessments of methodologies for the integration of genomic data.

 

Group composition

 

Contacts

Dott.ssa Cristina Battaglia (cristina.battaglia@unimi.it)
Skype: cristina.battaglia
Phone: +390250330421
Location: L.I.T.A Palace, via F. Cervi 93, 20090 Segrate (MI), Italy, 4th floor.
Skype: cristina.battaglia
Orcid ID: http://orcid.org/0000-0003-3025-9657
https://expertise.unimi.it/get/person/cristina-battaglia