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Department of

Medical Biotechnology and Translational Medicine

The Department of Medical Biotechnology and Translational Medicine, originated from matching interests and expertise in molecular and cellular sciences, sciences applied to medicine and clinical sciences, identifies research and teaching as two aspects to be integrated at most.

Cà Granda, facciata su via Festa del Perdono
 
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Biometra Seminars

BioMeTra Seminars 2019/2020

"Atypical Chemokine Receptors: From Silence to Sound. The ACKR2 case" is the title of the next seminar of the cycle "BioMeTra Seminars 2019/2020" will take place on July 9th 2020 at 2:30 pm on line

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Focus on  

HDAC8: a promising therapeutic target for Acute Myeloid Leukaemia

Low level of acetylation due to high expression of Histone deacetylases (HDACs) is observed in Acute Myeloid Leukemia (AML). In this work we demonstrated that forced expression of HDAC8 in zebrafish embryos induced an imbalance of haematopoiesis that can be rescued with a specific HDAC8 inhibitor.

Revealing in the primary cilium a novel therapeutic target for the treatment of Rett syndrome

We demonstrate in cellular and animal models of Rett syndrome (RTT) the occurrence of defects of primary cilium, a sensory antenna protruded by all vertebrate cells. Drugs acting at the primary cilium can improve some defects typical of RTT. Although we don’t want to define RTT as a ciliopathy we propose the primary cilium as a pharmacological target for novel therapeutic approaches.

BIOMETRA - edificio Farmacologia Medica  

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BIOMETRA - edificio Farmacologia Medica

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Via Vanvitelli, 32 - 20129 MILANO
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